FPIES is a clinical diagnosis, which means there are currently no tests to make or confirm the diagnosis. There are no standard treatment protocols, yet. Research and advancements are being made by doctors all over the world to advance the understanding of FPIES and to bring about better management strategies and outcomes for those affected by this condition.

We have compiled a list of some of the best and most recent medical articles for you or your doctors to review. We will continue to add to this index as more information is published and available.

Economic Impact of Childhood Fpies and IgE-Mediated Food Allergies.

Nowak-Wegrzyn, Anna H. et al. Economic Impact of Childhood Fpies and IgE-Mediated Food Allergies. Journal of Allergy and Clinical Immunology , Volume 137 , Issue 2 , AB240

The Differential Diagnosis of Food Protein-Induced Enteropathy by Intestinal Mucosal Pathology.

Kudo, Oka, Arai, Shimizu. The differential diagnosis of food protein-induced enteropathy by intestinal mucosal pathology. Nihon Shoni Arerugi Gakkaishi The Japanese Journal of Pediatric Allergy and Clinical Immunology 31(1):7-12 · January 2017.

ASD and Food Allergy. Harumi Jyonouchi. ASD and Food Allergy. Comprehensive Guide to Autism 2014, pp 1995-2013

Allergen Patch Test in Children With Food Allergy-Related Gastrointestinal Symptoms

Visitsunthorn, N.; Boonyaviwat, O.; Pacharn, P.; Piboonpocanun, O.; Vichyanond, P.Allergen Patch Test in Children With Food Allergy-related Gastrointestinal Symptoms.The Journal of Allergy and Clinical Immunology. February 2011; 127(2): AB181.

The Optimal Diagnostic Workup for Children with Suspected Food Allergy.

Berni Canani R, Di Costanzo M, Troncone R. The Optimal Diagnostic Workup for Children with Suspected Food Allergy. Nutrition. 2011 Oct;27(10):983-7.

Clinical Presentation of Food Allergy.

Food allergies as immune-mediated responses are discussed; and as occuring with varying clinical presentations.

Mansoor DK, Sharma HP. Clinical Presentation of Food Allergy. Pediatr Clin North Am. 2011 Apr;58(2):315-26, ix.

Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel

A full review of the latest guidelines for food allergy. See section 4.3.2 for FPIES information. NIAID-Sponsored Expert panel.

Guidelines for the Diagnosis and Management of Food Allergy in the United States: Report of the NIAID-Sponsored Expert Panel. The Journal of Allergy and Clinical Immunology. December 2010; 126 (6): S1-S58.

Food Allergy: Review, Classification and Diagnosis

Written in 2009, this article describes IgE allergy, oral tolerance and Non-IgE allergy in the context of rising food allergy diagnosis and treatments. Includes an excellent graph to illustrate IgE, Non-IgE and intolerance’s.

Cianferoni, A.; Spergel, J.M. Food Allergy: Review, Classification and Diagnosis. Allergology International. 2009; 58:457-466.

Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, food protein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediated cow’s milk allergy.

Maloney J, Nowak-Wegrzyn A. Educational clinical case series for pediatric allergy and immunology: allergic proctocolitis, foodprotein-induced enterocolitis syndrome and allergic eosinophilic gastroenteritis with protein-losing gastroenteropathy as manifestations of non-IgE-mediated cow’s milk allergy. Pediatr Allergy Immunol. 2007 Jun;18(4):360-7.

Rice-induced enterocolitis in an infant: TH1/TH2 cellular hypersensitivity and absent IgE reactivity.

Gray HC, Foy TM, Becker BA, Knutsen AP. Rice-induced enterocolitis in an infant: TH1/TH2 cellular hypersensitivity and absent IgE reactivity. Ann. Allergy Asthma Immunol. 93(6), 601—605 (2004).

The Mother of All Food Allergy

This article was written as a commentary to an article published in the same issue of The Journal of Pediatrics: “A consistent pattern of minor immunodeficiency and subtle enteropathy in children with multiple food allergy,” by a leading gastroenterologist in Eosinophilic disorders. It offers a perspective from the medical community.

Putnam, P. The Mother of All Food Allergy.The Journal of Pediatrics. July 2003; 143 (1): 7-9.

A Consistent Pattern of Minor Immunodeficiency and Subtle Enteropathy in Children with Multiple Food Allergy

Latcham et al. A Consistent Pattern of Minor Immunodeficiency and Subtle Enteropathy in Children with Multiple Food Allergy The Journal of Pediatrics 2003; 143:39-47.

**Of note, some online journal publications may be links to abstracts only with full access available for that journal’s subscribing members.

Page published: June 21, 2012  Last update: Feb.11, 2018. Copyright © 2012, The FPIES Foundation